practically by all phyla of both marine and terrestrial organisms, at any evolutionary
level. The extraordinary variety (and often complexity) of alkaloid structures and
biological properties have long intrigued natural product chemists (for structure
determination and biosynthetic studies), analytical chemists, and synthetic organic
chemists. Toxicologists, pharmacologists and pharmaceutical companies have used
and will certainly continue to use alkaloids as biological tools and/or as lead
compounds for development of new drugs.
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